Metformin accelerates zebrafish heart regeneration by inducing autophagy

Metformin is one of the most widely used drugs for type 2 diabetes and it also exhibits cardiovascular protective activity. However, the underlying mechanism of its action is not well understood. Here, we used an adult zebrafish model of heart cryoinjury, which mimics myocardial infarction in humans...

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Detalles Bibliográficos
Autores principales: Xie, Fangjing, Xu, Shisan, Lu, Yingying, Wong, Kin Fung, Sun, Lei, Hasan, Kazi Md Mahmudul, Ma, Alvin C. H., Tse, Gary, Manno, Sinai H. C., Tian, Li, Yue, Jianbo, Cheng, Shuk Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501080/
https://www.ncbi.nlm.nih.gov/pubmed/34625572
http://dx.doi.org/10.1038/s41536-021-00172-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501080/
https://www.ncbi.nlm.nih.gov/pubmed/34625572
http://dx.doi.org/10.1038/s41536-021-00172-w

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