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Metformin accelerates zebrafish heart regeneration by inducing autophagy
Metformin is one of the most widely used drugs for type 2 diabetes and it also exhibits cardiovascular protective activity. However, the underlying mechanism of its action is not well understood. Here, we used an adult zebrafish model of heart cryoinjury, which mimics myocardial infarction in humans...
Autores principales: | Xie, Fangjing, Xu, Shisan, Lu, Yingying, Wong, Kin Fung, Sun, Lei, Hasan, Kazi Md Mahmudul, Ma, Alvin C. H., Tse, Gary, Manno, Sinai H. C., Tian, Li, Yue, Jianbo, Cheng, Shuk Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501080/ https://www.ncbi.nlm.nih.gov/pubmed/34625572 http://dx.doi.org/10.1038/s41536-021-00172-w |
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