Concordance analysis of microsatellite instability status between polymerase chain reaction based testing and next generation sequencing for solid tumors

Various malignancies exhibit high microsatellite instability (MSI-H) or mismatch repair deficiency (dMMR). The MSI-IVD kit, a polymerase chain reaction (PCR)-based method, was the first tumor-agnostic companion diagnostic to detect MSI status in MSI-H solid tumors. Recently, next-generation sequenci...

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Detalles Bibliográficos
Autores principales: Shimozaki, Keitaro, Hayashi, Hideyuki, Tanishima, Shigeki, Horie, Sara, Chida, Akihiko, Tsugaru, Kai, Togasaki, Kazuhiro, Kawasaki, Kenta, Aimono, Eriko, Hirata, Kenro, Nishihara, Hiroshi, Kanai, Takanori, Hamamoto, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501090/
https://www.ncbi.nlm.nih.gov/pubmed/34625576
http://dx.doi.org/10.1038/s41598-021-99364-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501090/
https://www.ncbi.nlm.nih.gov/pubmed/34625576
http://dx.doi.org/10.1038/s41598-021-99364-z

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