Increase of 5-HT levels is induced both in mouse brain and HEK-293 cells following their exposure to a non-viral tryptophan hydroxylase construct

Tryptophan hydroxylase type 2 (Tph2) is the rate-limiting enzyme for serotonin (5-HT) biosynthesis in the brain. Dysfunctional Tph2 alters 5-HT biosynthesis, leading to a deficiency of 5-HT, which could have repercussions on human behavior. In the last decade, several studies have associated polymor...

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Detalles Bibliográficos
Autores principales: Tesoro-Cruz, Emiliano, Manuel-Apolinar, Leticia, Oviedo, Norma, Orozco-Suárez, Sandra, Crespo Ramírez, Minerva, Bekker-Méndez, Vilma Carolina, Aguirre-García, M. Magdalena, Rojas-Osornio, Sandra Angélica, Paredes-Cervantes, Vladimir, Pérez de la Mora, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501106/
https://www.ncbi.nlm.nih.gov/pubmed/34625528
http://dx.doi.org/10.1038/s41398-021-01634-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501106/
https://www.ncbi.nlm.nih.gov/pubmed/34625528
http://dx.doi.org/10.1038/s41398-021-01634-x

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