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Characterization of autofluorescence and quantitative protoporphyrin IX biomarkers for optical spectroscopy-guided glioma surgery

5-Aminolevulinic acid (5-ALA)-mediated fluorescence does not effectively depict low grade gliomas (LGG) or the infiltrative tumor portion of high-grade gliomas (HGG). While spectroscopy improves sensitivity and precision, this is currently limited by autofluorescence and a second protoporphyrin IX (...

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Detalles Bibliográficos
Autores principales: Black, David, Kaneko, Sadahiro, Walke, Anna, König, Simone, Stummer, Walter, Suero Molina, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501114/
https://www.ncbi.nlm.nih.gov/pubmed/34625597
http://dx.doi.org/10.1038/s41598-021-99228-6