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Interactions between PDA-associated polymorphisms and genetic ancestry alter ductus arteriosus gene expression

BACKGROUND: DNA polymorphisms in PTGIS and TFAP2B have been identified as risk factors for patent ductus arteriosus (PDA) in a population composed of preterm infants with European genetic ancestry but not in more genetically diverse populations. GOAL: To determine if the effects of TFAP2B and PTGIS...

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Detalles Bibliográficos
Autores principales: Clyman, Ronald I., Hills, Nancy K., Dagle, John M., Murray, Jeffrey C., Kelsey, Keegan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501158/
https://www.ncbi.nlm.nih.gov/pubmed/33837257
http://dx.doi.org/10.1038/s41390-021-01506-6