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Interactions between PDA-associated polymorphisms and genetic ancestry alter ductus arteriosus gene expression
BACKGROUND: DNA polymorphisms in PTGIS and TFAP2B have been identified as risk factors for patent ductus arteriosus (PDA) in a population composed of preterm infants with European genetic ancestry but not in more genetically diverse populations. GOAL: To determine if the effects of TFAP2B and PTGIS...
Autores principales: | Clyman, Ronald I., Hills, Nancy K., Dagle, John M., Murray, Jeffrey C., Kelsey, Keegan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501158/ https://www.ncbi.nlm.nih.gov/pubmed/33837257 http://dx.doi.org/10.1038/s41390-021-01506-6 |
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