Development and characterization of phasor-based analysis for FLIM to evaluate the metabolic and epigenetic impact of HER2 inhibition on squamous cell carcinoma cultures

Significance: Deranged metabolism and dysregulated growth factor signaling are closely associated with abnormal levels of proliferation, a recognized hallmark in tumorigenesis. Fluorescence lifetime imaging microscopy (FLIM) of endogenous nicotinamide adenine dinucleotide (NADH), a key metabolic coe...

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Detalles Bibliográficos
Autores principales: Pham, Dan L., Miller, Christina R., Myers, Molly S., Myers, Dominick M., Hansen, Laura A., Nichols, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2021
Materias:
Microscopy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501457/
https://www.ncbi.nlm.nih.gov/pubmed/34628733
http://dx.doi.org/10.1117/1.JBO.26.10.106501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501457/
https://www.ncbi.nlm.nih.gov/pubmed/34628733
http://dx.doi.org/10.1117/1.JBO.26.10.106501

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