Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR)

BACKGROUND: Duchenne muscular dystrophy (DMD) is a severe X-linked recessive disease caused by mutations in the dystrophin gene. Transplantation of myogenic stem cells holds great promise for treating muscular dystrophies. However, poor engraftment of myogenic stem cells limits the therapeutic effec...

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Detalles Bibliográficos
Autores principales: Elhussieny, Ahmed, Nogami, Ken’ichiro, Sakai-Takemura, Fusako, Maruyama, Yusuke, Takemura, Natsumi, Soliman, Wael Talaat, Takeda, Shin’ichi, Miyagoe-Suzuki, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501581/
https://www.ncbi.nlm.nih.gov/pubmed/34627382
http://dx.doi.org/10.1186/s13287-021-02594-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501581/
https://www.ncbi.nlm.nih.gov/pubmed/34627382
http://dx.doi.org/10.1186/s13287-021-02594-1

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