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TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus

The pathogenetic mechanisms underlying neuronal death and dysfunction in Alzheimer’s disease (AD) remain unclear. However, chronic neuroinflammation has been implicated in stimulating or exacerbating neuronal damage. The tumor necrosis factor (TNF) superfamily of cytokines are involved in many syste...

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Detalles Bibliográficos
Autores principales: Jayaraman, Anusha, Htike, Thein Than, James, Rachel, Picon, Carmen, Reynolds, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501605/
https://www.ncbi.nlm.nih.gov/pubmed/34625123
http://dx.doi.org/10.1186/s40478-021-01264-w