Comparison of the frequencies of ENU-induced point mutations in male germ cells and inherited germline mutations in their offspring

BACKGROUND: Gene mutations induced in germ cells may be transmitted to the next generation and cause adverse effects such as genetic diseases. Certain mutations may result in infertility or death in early development. Thus, the mutations may not be inheritable. However, the extent to which point mut...

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Detalles Bibliográficos
Autores principales: Masumura, Kenichi, Ando, Tomoko, Toyoda-Hokaiwado, Naomi, Ukai, Akiko, Nohmi, Takehiko, Honma, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501628/
https://www.ncbi.nlm.nih.gov/pubmed/34627396
http://dx.doi.org/10.1186/s41021-021-00216-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501628/
https://www.ncbi.nlm.nih.gov/pubmed/34627396
http://dx.doi.org/10.1186/s41021-021-00216-z

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