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Comparison of the frequencies of ENU-induced point mutations in male germ cells and inherited germline mutations in their offspring
BACKGROUND: Gene mutations induced in germ cells may be transmitted to the next generation and cause adverse effects such as genetic diseases. Certain mutations may result in infertility or death in early development. Thus, the mutations may not be inheritable. However, the extent to which point mut...
Autores principales: | Masumura, Kenichi, Ando, Tomoko, Toyoda-Hokaiwado, Naomi, Ukai, Akiko, Nohmi, Takehiko, Honma, Masamitsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501628/ https://www.ncbi.nlm.nih.gov/pubmed/34627396 http://dx.doi.org/10.1186/s41021-021-00216-z |
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