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Tanshinone IIA attenuates renal injury during hypothermic preservation via the MEK/ERK1/2/GSK-3β pathway

BACKGROUND: Oxidative stress-induced injury during hypothermic preservation is a universal problem that delays graft function and decrease the success of organ transplantation. Tanshinone IIA (Tan IIA) was reported to exhibit a variety of biochemical activities, including protection against oxidativ...

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Detalles Bibliográficos
Autores principales: Xu, Linhao, Xu, Yizhou, Zhu, Zhoujing, Gu, Huiquan, Chen, Chaofeng, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501657/
https://www.ncbi.nlm.nih.gov/pubmed/34625061
http://dx.doi.org/10.1186/s12906-021-03427-7