The spliceosome pathway activity correlates with reduced anti-tumor immunity and immunotherapy response, and unfavorable clinical outcomes in pan-cancer

Alterations in the spliceosome pathway (SP) have been associated with diverse human cancers. In this study, we explored associations of the SP activity with various clinical features, anti-tumor immune signatures, tumor immunity-related genomic and molecular features, and the response to immunothera...

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Detalles Bibliográficos
Autores principales: Chen, Zuobing, Chen, Canping, Li, Lin, Zhang, Tianfang, Wang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501672/
https://www.ncbi.nlm.nih.gov/pubmed/34667536
http://dx.doi.org/10.1016/j.csbj.2021.09.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501672/
https://www.ncbi.nlm.nih.gov/pubmed/34667536
http://dx.doi.org/10.1016/j.csbj.2021.09.029

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