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RhoA enhances osteosarcoma resistance to MPPa-PDT via the Hippo/YAP signaling pathway

BACKGROUND: Osteosarcoma (OS) is the most prevalent primary bone malignancy affecting adolescents, yet the emergence of chemoradiotherapeutic resistance has limited efforts to cure affected patients to date. Pyropheophorbide-α methyl ester-mediated photodynamic therapy (MPPa-PDT) is a recently devel...

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Detalles Bibliográficos
Autores principales: Zhan, Fangbiao, He, Tao, Chen, Zhiyu, Zuo, Qiang, Wang, Yang, Li, Qiaochu, Zhong, Shenxi, Ou, Yunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501741/
https://www.ncbi.nlm.nih.gov/pubmed/34627383
http://dx.doi.org/10.1186/s13578-021-00690-6