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RhoA enhances osteosarcoma resistance to MPPa-PDT via the Hippo/YAP signaling pathway
BACKGROUND: Osteosarcoma (OS) is the most prevalent primary bone malignancy affecting adolescents, yet the emergence of chemoradiotherapeutic resistance has limited efforts to cure affected patients to date. Pyropheophorbide-α methyl ester-mediated photodynamic therapy (MPPa-PDT) is a recently devel...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501741/ https://www.ncbi.nlm.nih.gov/pubmed/34627383 http://dx.doi.org/10.1186/s13578-021-00690-6 |