Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival

Integrin alpha 2 (ITGA2) promotes cancer metastasis through selective adhesion to ECM proteins; however, the specific contribution of integrin glycosylation remains uncertain. We provide evidence that ITGA2 is a highly glycosylated transmembrane protein expressed in ovarian cancer tissue and cell li...

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Detalles Bibliográficos
Autores principales: Huang, Yen-Lin, Liang, Ching-Yeu, Labitzky, Vera, Ritz, Danilo, Oliveira, Tiago, Cumin, Cécile, Estermann, Manuela, Lange, Tobias, Everest-Dass, Arun V., Jacob, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501769/
https://www.ncbi.nlm.nih.gov/pubmed/34646995
http://dx.doi.org/10.1016/j.isci.2021.103168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501769/
https://www.ncbi.nlm.nih.gov/pubmed/34646995
http://dx.doi.org/10.1016/j.isci.2021.103168

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