Cargando…

Structural and energetic analysis of metastable intermediate states in the E1P–E2P transition of Ca(2+)-ATPase

Sarcoplasmic reticulum (SR) Ca(2+)-ATPase transports two Ca(2+) ions from the cytoplasm to the SR lumen against a large concentration gradient. X-ray crystallography has revealed the atomic structures of the protein before and after the dissociation of Ca(2+), while biochemical studies have suggeste...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, Chigusa, Matsunaga, Yasuhiro, Jung, Jaewoon, Sugita, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501872/
https://www.ncbi.nlm.nih.gov/pubmed/34593638
http://dx.doi.org/10.1073/pnas.2105507118