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Structural and energetic analysis of metastable intermediate states in the E1P–E2P transition of Ca(2+)-ATPase
Sarcoplasmic reticulum (SR) Ca(2+)-ATPase transports two Ca(2+) ions from the cytoplasm to the SR lumen against a large concentration gradient. X-ray crystallography has revealed the atomic structures of the protein before and after the dissociation of Ca(2+), while biochemical studies have suggeste...
Autores principales: | Kobayashi, Chigusa, Matsunaga, Yasuhiro, Jung, Jaewoon, Sugita, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501872/ https://www.ncbi.nlm.nih.gov/pubmed/34593638 http://dx.doi.org/10.1073/pnas.2105507118 |
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