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Mechanistic insights into central spindle assembly mediated by the centralspindlin complex

The central spindle spatially and temporally regulates the formation of division plane during cytokinesis in animal cells. The heterotetrameric centralspindlin complex bundles microtubules to assemble the central spindle, the mechanism of which is poorly understood. Here, we determined the crystal s...

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Detalles Bibliográficos
Autores principales: Pan, Han, Guan, Ruifang, Zhao, Ruixue, Ou, Guangshuo, Chen, Zhucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501884/
https://www.ncbi.nlm.nih.gov/pubmed/34588311
http://dx.doi.org/10.1073/pnas.2112039118