Joint modelling of multivariate longitudinal clinical laboratory safety outcomes, concomitant medication and clinical adverse events: application to artemisinin-based treatment during pregnancy clinical trial

BACKGROUND: In drug trials, clinical adverse events (AEs), concomitant medication and laboratory safety outcomes are repeatedly collected to support drug safety evidence. Despite the potential correlation of these outcomes, they are typically analysed separately, potentially leading to misinformatio...

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Detalles Bibliográficos
Autores principales: Patson, Noel, Mukaka, Mavuto, D’Alessandro, Umberto, Chapotera, Gertrude, Mwapasa, Victor, Mathanga, Don, Kazembe, Lawrence, Laufer, Miriam K., Chirwa, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501924/
https://www.ncbi.nlm.nih.gov/pubmed/34627141
http://dx.doi.org/10.1186/s12874-021-01412-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501924/
https://www.ncbi.nlm.nih.gov/pubmed/34627141
http://dx.doi.org/10.1186/s12874-021-01412-9

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