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A formulated poly (I:C)/CCL21 as an effective mucosal adjuvant for gamma-irradiated influenza vaccine

BACKGROUND: Several studies on gamma-irradiated influenza A virus (γ-Flu) have revealed its superior efficacy for inducing homologous and heterologous virus-specific immunity. However, many inactivated vaccines, notably in nasal delivery, require adjuvants to increase the quality and magnitude of va...

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Detalles Bibliográficos
Autores principales: Sabbaghi, Ailar, Malek, Masoud, Abdolahi, Sara, Miri, Seyed Mohammad, Alizadeh, Leila, Samadi, Mehdi, Mohebbi, Seyed Reza, Ghaemi, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501930/
https://www.ncbi.nlm.nih.gov/pubmed/34627297
http://dx.doi.org/10.1186/s12985-021-01672-3