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Codependency and mutual exclusivity for gene community detection from sparse single-cell transcriptome data

Single-cell RNA-seq (scRNA-seq) can be used to characterize cellular heterogeneity in thousands of cells. The reconstruction of a gene network based on coexpression patterns is a fundamental task in scRNA-seq analyses, and the mutual exclusivity of gene expression can be critical for understanding s...

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Detalles Bibliográficos
Autores principales: Nakajima, Natsu, Hayashi, Tomoatsu, Fujiki, Katsunori, Shirahige, Katsuhiko, Akiyama, Tetsu, Akutsu, Tatsuya, Nakato, Ryuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501962/
https://www.ncbi.nlm.nih.gov/pubmed/34291282
http://dx.doi.org/10.1093/nar/gkab601