capCLIP: a new tool to probe translational control in human cells through capture and identification of the eIF4E–mRNA interactome

Translation of eukaryotic mRNAs begins with binding of their m(7)G cap to eIF4E, followed by recruitment of other translation initiation factor proteins. We describe capCLIP, a novel method to comprehensively capture and quantify the eIF4E (eukaryotic initiation factor 4E) ‘cap-ome’ and apply it to...

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Detalles Bibliográficos
Autores principales: Jensen, Kirk B, Dredge, B Kate, Toubia, John, Jin, Xin, Iadevaia, Valentina, Goodall, Gregory J, Proud, Christopher G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501963/
https://www.ncbi.nlm.nih.gov/pubmed/34255842
http://dx.doi.org/10.1093/nar/gkab604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501963/
https://www.ncbi.nlm.nih.gov/pubmed/34255842
http://dx.doi.org/10.1093/nar/gkab604

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