Suppression of liquid–liquid phase separation by 1,6-hexanediol partially compromises the 3D genome organization in living cells

Liquid–liquid phase separation (LLPS) contributes to the spatial and functional segregation of molecular processes within the cell nucleus. However, the role played by LLPS in chromatin folding in living cells remains unclear. Here, using stochastic optical reconstruction microscopy (STORM) and Hi-C...

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Detalles Bibliográficos
Autores principales: Ulianov, Sergey V, Velichko, Artem K, Magnitov, Mikhail D, Luzhin, Artem V, Golov, Arkadiy K, Ovsyannikova, Natalia, Kireev, Igor I, Gavrikov, Alexey S, Mishin, Alexander S, Garaev, Azat K, Tyakht, Alexander V, Gavrilov, Alexey A, Kantidze, Omar L, Razin, Sergey V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501969/
https://www.ncbi.nlm.nih.gov/pubmed/33836078
http://dx.doi.org/10.1093/nar/gkab249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501969/
https://www.ncbi.nlm.nih.gov/pubmed/33836078
http://dx.doi.org/10.1093/nar/gkab249

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