Divergent degeneration of creA antitoxin genes from minimal CRISPRs and the convergent strategy of tRNA-sequestering CreT toxins

Aside from providing adaptive immunity, type I CRISPR-Cas was recently unearthed to employ a noncanonical RNA guide (CreA) to transcriptionally repress an RNA toxin (CreT). Here, we report that, for most archaeal and bacterial CreTA modules, the creA gene actually carries two flanking ‘CRISPR repeat...

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Detalles Bibliográficos
Autores principales: Cheng, Feiyue, Wang, Rui, Yu, Haiying, Liu, Chao, Yang, Jun, Xiang, Hua, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501985/
https://www.ncbi.nlm.nih.gov/pubmed/34551428
http://dx.doi.org/10.1093/nar/gkab821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501985/
https://www.ncbi.nlm.nih.gov/pubmed/34551428
http://dx.doi.org/10.1093/nar/gkab821

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