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Structure of an inactive RNA polymerase II dimer

Eukaryotic gene transcription is carried out by three RNA polymerases: Pol I, Pol II and Pol III. Although it has long been known that Pol I can form homodimers, it is unclear whether and how the two other RNA polymerases dimerize. Here we present the cryo-electron microscopy (cryo-EM) structure of...

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Detalles Bibliográficos
Autores principales: Aibara, Shintaro, Dienemann, Christian, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501987/
https://www.ncbi.nlm.nih.gov/pubmed/34530439
http://dx.doi.org/10.1093/nar/gkab783