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Comprehensive characterization of somatic variants associated with intronic polyadenylation in human cancers

Somatic single nucleotide variants (SNVs) in cancer genome affect gene expression through various mechanisms depending on their genomic location. While somatic SNVs near canonical splice sites have been reported to cause abnormal splicing of cancer-related genes, whether these SNVs can affect gene e...

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Detalles Bibliográficos
Autores principales: Zhao, Zhaozhao, Xu, Qiushi, Wei, Ran, Huang, Leihuan, Wang, Weixu, Wei, Gang, Ni, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501991/
https://www.ncbi.nlm.nih.gov/pubmed/34508351
http://dx.doi.org/10.1093/nar/gkab772