rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosis

OBJECTIVE: To investigate the mutations within the whole rpoB gene of Mycobacterium tuberculosis and analyze their effects on rifampin (RIF) resistance based on crystal structure. METHODS: We sequenced the entire rpoB gene in 175 tuberculosis isolates and quantified their minimum inhibitory concentr...

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Detalles Bibliográficos
Autores principales: Li, Ma-chao, Lu, Jie, Lu, Yao, Xiao, Tong-yang, Liu, Hai-can, Lin, Shi-qiang, Xu, Da, Li, Gui-lian, Zhao, Xiu-qin, Liu, Zhi-guang, Zhao, Li-li, Wan, Kang-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502021/
https://www.ncbi.nlm.nih.gov/pubmed/34675557
http://dx.doi.org/10.2147/IDR.S333433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502021/
https://www.ncbi.nlm.nih.gov/pubmed/34675557
http://dx.doi.org/10.2147/IDR.S333433

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