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rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosis
OBJECTIVE: To investigate the mutations within the whole rpoB gene of Mycobacterium tuberculosis and analyze their effects on rifampin (RIF) resistance based on crystal structure. METHODS: We sequenced the entire rpoB gene in 175 tuberculosis isolates and quantified their minimum inhibitory concentr...
Autores principales: | Li, Ma-chao, Lu, Jie, Lu, Yao, Xiao, Tong-yang, Liu, Hai-can, Lin, Shi-qiang, Xu, Da, Li, Gui-lian, Zhao, Xiu-qin, Liu, Zhi-guang, Zhao, Li-li, Wan, Kang-lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502021/ https://www.ncbi.nlm.nih.gov/pubmed/34675557 http://dx.doi.org/10.2147/IDR.S333433 |
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