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JAK2 and TET2 Mutation in Polycythemia Vera

The Ten-Eleven Translocation-2 (TET2) gene, located on chromosome 4q24, has been implicated in hematological malignancies. The TET2 gene shows mutations in variable myeloid malignancies with the involvement of 15% of myeloproliferative neoplasms (MPNs). The inactivation of the TET2 gene in both mice...

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Detalles Bibliográficos
Autores principales: Padda, Jaskamal, Khalid, Khizer, Yadav, Jayant, Almanie, Abdulelah H, Mehta, Krutagni Adwait, Al Hennawi, Hussam, Boddeti, Nymisha L, Campos, Victor Yosef Melt, Jean-Charles, Gutteridge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502023/
https://www.ncbi.nlm.nih.gov/pubmed/34660059
http://dx.doi.org/10.7759/cureus.17854