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Synthesis of Novel Pinocembrin Amino Acid Derivatives and Their Antiaging Effect on Caenorhabditis elegans via the Modulating DAF-16/FOXO

PURPOSE: Pinocembrin is a dihydroflavonoid, which is widely found in several plant species. Although pinocembrin has good pharmacological activity, it has poor water solubility and low bioavailability. Therefore, we have modified the structure of pinocembrin with a combination of different amino aci...

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Detalles Bibliográficos
Autores principales: Wang, Wenqi, Feng, Xin, Du, Yu, Liu, Cen, Pang, Xinxin, Jiang, Kunxiu, Wang, Xirui, Liu, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502036/
https://www.ncbi.nlm.nih.gov/pubmed/34675482
http://dx.doi.org/10.2147/DDDT.S330223