Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs

Nucleic acid therapeutics are developing into precise medicines that can manipulate specific genes. However, the development of safe and effective delivery system for the target cells has remained a challenge. Lipid nanoparticles (LNPs) have provided a revolutionary delivery system that can ensure m...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuta, Ishihara, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502116/
https://www.ncbi.nlm.nih.gov/pubmed/34757287
http://dx.doi.org/10.1016/j.dmpk.2021.100424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502116/
https://www.ncbi.nlm.nih.gov/pubmed/34757287
http://dx.doi.org/10.1016/j.dmpk.2021.100424

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