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A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori

ABSTRACT: Due to the growing number of Helicobacter pylori strains resistant to currently available antibiotics, there is an urgent need to design new drugs utilizing different molecular mechanisms than those that have been used up to now. Enzymes of the purine salvage pathway are possible targets o...

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Detalles Bibliográficos
Autores principales: Wojtyś, Marta Ilona, Jaźwiec, Radosław, Kazazić, Saša, Leščić Ašler, Ivana, Knežević, Petar, Aleksić Sabo, Verica, Luić, Marija, Jagusztyn-Krynicka, Elżbieta Katarzyna, Bzowska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502122/
https://www.ncbi.nlm.nih.gov/pubmed/34562116
http://dx.doi.org/10.1007/s00253-021-11510-9