Oxy210, a novel inhibitor of hedgehog and TGF‐β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice

AIMS: Non‐alcoholic steatohepatitis (NASH) is associated with increased overall morbidity and mortality in non‐alcoholic fatty liver disease (NAFLD) patients. Liver fibrosis is the strongest prognostic factor for clinical outcomes, liver‐related mortality and liver transplantation. Currently, no sin...

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Detalles Bibliográficos
Autores principales: Hui, Simon T., Wang, Feng, Stappenbeck, Frank, French, Samuel W., Magyar, Clara E., Parhami, Farhad, Lusis, Aldons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502222/
https://www.ncbi.nlm.nih.gov/pubmed/34505423
http://dx.doi.org/10.1002/edm2.296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502222/
https://www.ncbi.nlm.nih.gov/pubmed/34505423
http://dx.doi.org/10.1002/edm2.296

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