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Oxy210, a novel inhibitor of hedgehog and TGF‐β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice
AIMS: Non‐alcoholic steatohepatitis (NASH) is associated with increased overall morbidity and mortality in non‐alcoholic fatty liver disease (NAFLD) patients. Liver fibrosis is the strongest prognostic factor for clinical outcomes, liver‐related mortality and liver transplantation. Currently, no sin...
Autores principales: | Hui, Simon T., Wang, Feng, Stappenbeck, Frank, French, Samuel W., Magyar, Clara E., Parhami, Farhad, Lusis, Aldons J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502222/ https://www.ncbi.nlm.nih.gov/pubmed/34505423 http://dx.doi.org/10.1002/edm2.296 |
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