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Telomere shortening causes distinct cell division regimes during replicative senescence in Saccharomyces cerevisiae
BACKGROUND: Telomerase-negative cells have limited proliferation potential. In these cells, telomeres shorten until they reach a critical length and induce a permanently arrested state. This process called replicative senescence is associated with genomic instability and participates in tissue and o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502270/ https://www.ncbi.nlm.nih.gov/pubmed/34627377 http://dx.doi.org/10.1186/s13578-021-00693-3 |