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Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15

BACKGROUND: Enhanced metabolic plasticity and diversification of energy production is a hallmark of highly proliferative breast cancers. This contributes to poor pharmacotherapy efficacy, recurrence, and metastases. We have previously identified a mitochondrial-targeted furazano[3,4-b]pyrazine named...

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Detalles Bibliográficos
Autores principales: Zunica, Elizabeth R. M., Axelrod, Christopher L., Cho, Eunhan, Spielmann, Guillaume, Davuluri, Gangarao, Alexopoulos, Stephanie J., Beretta, Martina, Hoehn, Kyle L., Dantas, Wagner S., Stadler, Krisztian, King, William T., Pergola, Kathryn, Irving, Brian A., Langohr, Ingeborg M., Yang, Shengping, Hoppel, Charles L., Gilmore, L. Anne, Kirwan, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502397/
https://www.ncbi.nlm.nih.gov/pubmed/34627389
http://dx.doi.org/10.1186/s40170-021-00274-5