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Integrative eQTL-weighted hierarchical Cox models for SNP-set based time-to-event association studies

BACKGROUND: Integrating functional annotations into SNP-set association studies has been proven a powerful analysis strategy. Statistical methods for such integration have been developed for continuous and binary phenotypes; however, the SNP-set integrative approaches for time-to-event or survival o...

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Detalles Bibliográficos
Autores principales: Lu, Haojie, Wei, Yongyue, Jiang, Zhou, Zhang, Jinhui, Wang, Ting, Huang, Shuiping, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502405/
https://www.ncbi.nlm.nih.gov/pubmed/34627275
http://dx.doi.org/10.1186/s12967-021-03090-z