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Integrative eQTL-weighted hierarchical Cox models for SNP-set based time-to-event association studies
BACKGROUND: Integrating functional annotations into SNP-set association studies has been proven a powerful analysis strategy. Statistical methods for such integration have been developed for continuous and binary phenotypes; however, the SNP-set integrative approaches for time-to-event or survival o...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502405/ https://www.ncbi.nlm.nih.gov/pubmed/34627275 http://dx.doi.org/10.1186/s12967-021-03090-z |