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The detection of specific hypermethylated WIF1 and NPY genes in circulating DNA by crystal digital PCR™ is a powerful new tool for colorectal cancer diagnosis and screening

BACKGROUND: In oncology, liquid biopsy is of major relevance from theranostic point of view. The searching for mutations in circulating tumor DNA (ctDNA) in case of colorectal cancers (CRCs) allows the optimization of patient care. In this context, independent of mutation status biomarkers are requi...

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Detalles Bibliográficos
Autores principales: Overs, Alexis, Flammang, Mylène, Hervouet, Eric, Bermont, Laurent, Pretet, Jean-Luc, Christophe, Borg, Selmani, Zohair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502418/
https://www.ncbi.nlm.nih.gov/pubmed/34627187
http://dx.doi.org/10.1186/s12885-021-08816-2