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Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

BACKGROUND: Plasma hyaluronan concentrations are increased during sepsis but underlying mechanisms leading to high plasma hyaluronan concentration are poorly understood. In this study we evaluate the roles of plasma hyaluronan, effective plasma hyaluronidase (HYAL) activity and its endogenous plasma...

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Detalles Bibliográficos
Autores principales: van der Heijden, Jaap, Kolliopoulos, Constantinos, Skorup, Paul, Sallisalmi, Marko, Heldin, Paraskevi, Hultström, Michael, Tenhunen, Jyrki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502523/
https://www.ncbi.nlm.nih.gov/pubmed/34632531
http://dx.doi.org/10.1186/s40635-021-00418-3