Analytical Similarity Assessment of ABP 959 in Comparison with Eculizumab Reference Product

BACKGROUND: ABP 959 is one of the first proposed biosimilars to eculizumab reference product (RP), a recombinant IgG2/4(Ƙ) monoclonal antibody (mAb) that binds human C5 complement protein and inhibits C5 cleavage to C5a and C5b, preventing the generation of the terminal complement complex C5b-9. Ecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Hutterer, Katariina M., Ip, Anna, Kuhns, Scott, Cao, Shawn, Wikström, Mats, Liu, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502742/
https://www.ncbi.nlm.nih.gov/pubmed/34296421
http://dx.doi.org/10.1007/s40259-021-00492-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502742/
https://www.ncbi.nlm.nih.gov/pubmed/34296421
http://dx.doi.org/10.1007/s40259-021-00492-9

Ejemplares similares