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β2-and β3-Adrenergic Receptors Contribute to Cancer-Evoked Pain in a Mouse Model of Osteosarcoma via Modulation of Neural Macrophages

The mechanisms involved in the development and maintenance of cancer pain remain largely unidentified. Recently, it has been reported that β-adrenergic receptors (β-ARs), mainly β2-and β3-ARs, contribute to tumor proliferation and progression and may favor cancer-associated pain and neuroinflammatio...

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Detalles Bibliográficos
Autores principales: Bruno, Gennaro, De Logu, Francesco, Souza Monteiro de Araujo, Daniel, Subbiani, Angela, Lunardi, Federica, Rettori, Sofia, Nassini, Romina, Favre, Claudio, Calvani, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502859/
https://www.ncbi.nlm.nih.gov/pubmed/34646131
http://dx.doi.org/10.3389/fphar.2021.697912