The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination

Cells must replicate and segregate their DNA to daughter cells accurately to maintain genome stability and prevent cancer. DNA replication is usually fast and accurate, with intrinsic (proofreading) and extrinsic (mismatch repair) error-correction systems. However, replication forks slow or stop whe...

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Detalles Bibliográficos
Autores principales: Nickoloff, Jac A., Sharma, Neelam, Taylor, Lynn, Allen, Sage J., Hromas, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502867/
https://www.ncbi.nlm.nih.gov/pubmed/34646312
http://dx.doi.org/10.3389/fgene.2021.748033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502867/
https://www.ncbi.nlm.nih.gov/pubmed/34646312
http://dx.doi.org/10.3389/fgene.2021.748033

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