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The Ganglioside Monosialotetrahexosylganglioside Protects Auditory Hair Cells Against Neomycin-Induced Cytotoxicity Through Mitochondrial Antioxidation: An in vitro Study

Neomycin is a common ototoxic aminoglycoside antibiotic that causes sensory hearing disorders worldwide, and monosialotetrahexosylganglioside (GM1) is reported to have antioxidant effects that protect various cells. However, little is known about the effect of GM1 on neomycin-induced hair cell (HC)...

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Detalles Bibliográficos
Autores principales: Li, Yujin, Li, Ao, Wang, Chao, Jin, Xin, Zhang, Yaoting, Lu, Ling, Wang, Shou-Lin, Gao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502895/
https://www.ncbi.nlm.nih.gov/pubmed/34646124
http://dx.doi.org/10.3389/fncel.2021.751867