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An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification

Gastric carcinoma (GC) is a severe tumor of the digestive tract with high morbidity and mortality and poor prognosis, for which novel treatment options are urgently needed. Compound Kushen injection (CKI), a classical injection of Chinese medicine, has been widely used to treat various tumors in cli...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Wu, Chao, Zhao, Chongjun, Huang, Zhihong, Lu, Shan, Fan, Xiaotian, Tan, Yingying, Stalin, Antony, You, Rongli, Liu, Xinkui, Zhang, Jingyuan, Wu, Zhishan, Wu, Jiarui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502965/
https://www.ncbi.nlm.nih.gov/pubmed/34646828
http://dx.doi.org/10.3389/fcell.2021.742421