PRDM12 Is Transcriptionally Active and Required for Nociceptor Function Throughout Life

PR domain-containing member 12 (PRDM12) is a key developmental transcription factor in sensory neuronal specification and survival. Patients with rare deleterious variants in PRDM12 are born with congenital insensitivity to pain (CIP) due to the complete absence of a subtype of peripheral neurons th...

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Detalles Bibliográficos
Autores principales: Kokotović, Tomislav, Langeslag, Michiel, Lenartowicz, Ewelina M., Manion, John, Fell, Christopher W., Alehabib, Elham, Tafakhori, Abbas, Darvish, Hossein, Bellefroid, Eric J., Neely, G. Gregory, Kress, Michaela, Penninger, Josef M., Nagy, Vanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502974/
https://www.ncbi.nlm.nih.gov/pubmed/34646120
http://dx.doi.org/10.3389/fnmol.2021.720973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502974/
https://www.ncbi.nlm.nih.gov/pubmed/34646120
http://dx.doi.org/10.3389/fnmol.2021.720973

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