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Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma

One contributor to the high mortality of osteosarcoma is its reduced sensitivity to chemotherapy, but the mechanism involved is unclear. Improving the sensitivity of osteosarcoma to chemotherapy is urgently needed to improve patient survival. We found that chemotherapy triggered apoptosis of human o...

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Detalles Bibliográficos
Autores principales: Tang, Zhen, Wei, Xinghui, Li, Tian, Wang, Wei, Wu, Hao, Dong, Hui, Liu, Yichao, Wei, Feilong, Shi, Lei, Li, Xiaokang, Guo, Zheng, Xiao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502982/
https://www.ncbi.nlm.nih.gov/pubmed/34646824
http://dx.doi.org/10.3389/fcell.2021.722960