Impact of Specific N-Glycan Modifications on the Use of Plant-Produced SARS-CoV-2 Antigens in Serological Assays

The receptor binding domain (RBD) of the SARS-CoV-2 spike protein plays a key role in the virus-host cell interaction, and viral infection. The RBD is a major target for neutralizing antibodies, whilst recombinant RBD is commonly used as an antigen in serological assays. Such assays are essential to...

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Detalles Bibliográficos
Autores principales: Schwestka, Jennifer, König-Beihammer, Julia, Shin, Yun-Ji, Vavra, Ulrike, Kienzl, Nikolaus F., Grünwald-Gruber, Clemens, Maresch, Daniel, Klausberger, Miriam, Laurent, Elisabeth, Stadler, Maria, Manhart, Gabriele, Huber, Jasmin, Hofner, Manuela, Vierlinger, Klemens, Weinhäusel, Andreas, Swoboda, Ines, Binder, Christoph J., Gerner, Wilhelm, Grebien, Florian, Altmann, Friedrich, Mach, Lukas, Stöger, Eva, Strasser, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503525/
https://www.ncbi.nlm.nih.gov/pubmed/34646292
http://dx.doi.org/10.3389/fpls.2021.747500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503525/
https://www.ncbi.nlm.nih.gov/pubmed/34646292
http://dx.doi.org/10.3389/fpls.2021.747500

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