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Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage

Energy metabolism and extracellular matrix (ECM) function together orchestrate and maintain tissue organization, but crosstalk between these processes is poorly understood. Here, we used single-cell RNA-Seq (scRNA-Seq) analysis to uncover the importance of the mitochondrial respiratory chain for ECM...

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Detalles Bibliográficos
Autores principales: Bubb, Kristina, Holzer, Tatjana, Nolte, Janica L., Krüger, Marcus, Wilson, Richard, Schlötzer-Schrehardt, Ursula, Brinckmann, Jürgen, Altmüller, Janine, Aszodi, Attila, Fleischhauer, Lutz, Clausen-Schaumann, Hauke, Probst, Kristina, Brachvogel, Bent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503590/
https://www.ncbi.nlm.nih.gov/pubmed/34560099
http://dx.doi.org/10.1016/j.jbc.2021.101224